The story of Amiflex® and Amiflex® 2.0 in the USA
In spring 2023, we launched Amiflex, the first registered amitraz “flash” treatment in the U.S. without temperature constraints during use. However, Amiflex was classified under RUP (Restricted Use Pesticides) status, meaning it can only be applied by certified users who have completed specialized training and are licensed by state or federal authorities for using such products with restricted use.
Now, driven by our commitment to offering a more accessible, a user certification-free solution in the USA, we took decisive action and introduced a fully accessible treatment for all beekeepers – Amiflex 2.0 – delivering the same trusted performance as the original Amiflex.
The formulation, packaging, and conditions of use remain totally unchanged from the original Amiflex® except from the removal of RUP license requirement.
Following EPA’s federal approval, Amiflex 2.0 will soon be distributed to beekeepers across the United States, in accordance with local state registrations. As of February 4, 2026, the following states have approved Amiflex 2.0: Alaska (AK), Arizona (AZ), Arkansas (AR), Colorado (CO), Connecticut (CT), Delaware (DE), Georgia (GA), Idaho (ID), Iowa (IA), Kansas (KS), Kentucky (KY), Louisiana (LA), Maine (ME), Massachusetts (MA), Michigan (MI), Mississippi (MS), Missouri (MO), Nebraska (NE), Nevada (NV), New Jersey (NJ), New Mexico (NM), New York (NY), North Carolina (NC), North Dakota (ND), Ohio (OH), Oklahoma (OK), Pennsylvania (PA), Rhode Island (RI), South Carolina (SC), Tennessee (TN), Texas (TX), Utah (UT), Vermont (VT), Virginia (VA), Washington (WA), West Virginia (WV), Wisconsin (WI), Wyoming (WY).
We will keep you informed as soon as it becomes available through your distributors.
When can I use Amiflex® / Amiflex® 2.0?
Amiflex / Amiflex 2.0 is a 7-day treatment that can be applied once to four times per year per colony.
This treatment offers high flexibility, allowing application before, after, and between honey flows, as long as the bees are active in the hives, with no withdrawal period after treatment. Please note that treatment must always be carried out without honey supers.
Even when brood is present, Amiflex / Amiflex 2.0 delivers a rapid knock-down effect on varroa mites, making it an effective solution when quick mite reduction is needed.
In case of high infestation, up to two consecutive applications may be carried out, with a 7-day interval between treatments. Please keep in mind that no more than four applications may be conducted per year.
Amiflex / Amiflex 2.0 can also be applied at the end of the season, just before a slow-release treatment. Used this way, it provides an initial knock-down effect, helping to prepare honey bee colonies for a successful overwintering. Combining a flash treatment with a slow-release treatment ensures both fast mite reduction and long-term control.
Please note that Amiflex / Amiflex 2.0 does not replace long-acting treatments. It is designed as an additional tool within an integrated varroa control strategy.
Ready-To-Use for maximum convenience
Amiflex / Amiflex 2.0 is quick and easy to apply. Simply insert the cartridge into the dosing gun – no preparation or mixing or extra equipment needed!
The included dosing gun delivers a precise 3mL dose per application. Apply 2 doses (6mL) per single-body hive or 4 doses (12mL) per double-body hive.
Apply 2 doses of 3mL of Amiflex® / Amiflex® 2.0 gel per bee box. It means a total of 6mL for a single-body hive, and 12mL for a double-body hive.
Amiflex / Amiflex 2.0 is available in two formats:
- Starter Pack: 1 dosing gun, 10 cartridges (120mL each), 400 wooden supports.
- Refill Pack: 10 cartridges (120mL each), 400 wooden supports.
Each pack treats 100 (double brood box) to 200 hives (single brood box).
Restricted Use Pesticide Status – only applicable for Amiflex® in the USA
The RUP (Restricted Use Pesticides) status implies that these pesticides can only be used by certified applicators who have completed specialized training and are licensed by the state or federal government. This is to ensure that RUPs are applied in a safe and effective manner.
If you are interested in learning more about pesticide safety regulations and certification programs in your state, the EPA provides a comprehensive list of state pesticide safety education programs on their website.
Here is a PDF containing direct links to the Pesticide Use License programs for each state.
Visit our Amiflex / Amiflex 2.0 FAQ
Find quick, clear and practical answers to the most common questions about Amiflex. Our FAQ has been designed to help beekeepers ensure safe and effective treatment while protecting colony health.
Amiflex is registered under RUP status (Restricted Use Pesticide). The “Restricted Use” classification restricts a product, or its uses, to use by a certified applicator or someone under the certified applicator’s direct supervision.
AFP-11-US-N01-11/25